Friday, July 17, 2020

Discovery of a new particle: A Charming Tetraquark

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Hardi Talwani

Article Title

Discovery of a new particle: A Charming Tetraquark

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Global Views 360

Publication Date

July 17, 2020

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The Large Hadron Collider

The Large Hadron Collider | Source: Anna Pantelia via CERN

While the world is horrified by the novel Coronavirus, scientists at the European Centre for Nuclear Research (CERN) announced the discovery of a never seen before tetraquark. Any finding in particle physics is a phenomenal one because it could tell us a lot about the origins of the universe and how everything came to be. And this discovery is quite charming and quarky (quirky).

Quarks are the elementary particles so any further division of these particles is not possible. This means everything in the universe is ultimately a combination of Quarks. Any new discovery of Quarks  therefore increase our understanding about the origin of universe

When three Quarks come together, they form familiar particles known as Baryons, for instance, protons and neutrons, found in the nucleus of an atom. A tetraquark, in particle physics, is an exotic meson composed of four quarks.

Murray Gell-Mann, recipient of the 1969 Nobel Prize in Physics for his work on the theory of Elementary particles, chose the name ‘Quark’. Another scientist,  George Zweig from CERN also proposed the Quark theory independently of Gell-Mann.

All the new particles are detected using particle accelerators where particles are accelerated at almost the speed of light and collide to look into their subsets. It is like knocking two rocks together so that they break into smaller constituents.

The most recent tetraquark, named X (6900) was discovered by CERN physicists while working on LHCb (Large Hadron Collider beauty experiment). The already known tetraquarks contain a particular combination of two relatively heavy quarks and two light Quarks. On the other hand X(6900) consists of four heavy Quarks: two Quarks and two anti-Quarks.

This exclusive particle made of unusual combinations is a perfect setting for understanding the fundamental force of nature known as Strong Interaction. The strong force is vital to comprehend as it binds together protons, neutrons and the nucleus that ultimately make up matter. Another perk of X(6900)  is its relatively heavy mass, so these are simpler to look at and are more stable as compared to notoriously fast moving-lighter ones.

The paper written by 800 scientists is yet to be peer-reviewed. The bump observed has a statistical significance of more than five sigma (standard deviations) that is good enough to claim the discovery of a new particle.

In any scenario, this unusual discovery will serve as a piece for completing the puzzle of our universe while serving as evidence of the presence of new particles not yet found.

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February 4, 2021 4:48 PM

The Coronavirus Disease

Severe acute respiratory syndrome-Coronavirus 2 (SARS-CoV-2) is a novel virus from the family of coronaviruses which causes COVID-19 i.e. Coronavirus Disease-2019. It is the successor of the SARS-CoV-1 which caused the SARS outbreak in the year 2003-2004. This is a positive-sense single-stranded RNA virus which has rapid mutation properties.

The etymology of the name suggests that 'Corona' comes from the Latin word corōna meaning crown, garland, or a wreath. When seen under an Electron Microscope, the virion which has a diameter of 50-200 nanometres looks like the solar corona hence named Coronavirus.

When the virus enters the body; it attaches itself to the binding site or the ACE 2 receptors of healthy lung cells through its spike protein. Then it enters the cell via this attachment and causes apoptosis or cell death. The virus also affects organs other than lungs such as the brain, heart and kidneys. The multiple impact points make it problematic for the researchers to create a vaccine in addition to its rapid mutation properties.

The disease might have a zoonotic origin i.e. the transmission occurs from animals to humans. On comparing the genomic sequences the Human Coronavirus strain is found to be 96% identical to Bat Coronavirus samples and 92% similar to the Pangolins samples. Human transmission of the disease takes place via air droplets when the infected person is coughing, sneezing or talking.

The first cases of this respiratory illness were reported to the World Health Organization (WHO) from Wuhan City, Hubei Province, China, on 31 December 2019. It is the first severe outbreak since the 2009 H1N1 Influenza Pandemic. Initially, it was supposed that the site of origination is Huanan Seafood Wholesale Market but, in May 2020 the negative samples tested, by  Chinese Center for Disease Control and Prevention, from the livestock market suggested that it was the site of the super spreading of the virus.

SARS-CoV-2 is known to have an average reproduction number of 2.2-2.6 which means that, on an average, one infected person can spread the infection to 2-3 people. Although if measures like social distancing are put into use, to reduce the exposure of the infected population, it leads to a significant reduction in transmission rates. The infection fatality rate (IFR) of COVID-19 in various studies till 16th June 2020 was projected to range 0.60% to 1% of infected people . However few studies suggested the IFR as high as 3.6%.

The testing of an individual takes place through a method known as real-time Reverse transcription Polymerization Chain reaction (rRT-PCR). The process of obtaining strains and testing the patients usually involves nasal swabs or sputum swabs; the results come in within a span of a few hours to a couple of days.

Currently, there are no known vaccines available for the virus or any specific antiviral treatments, but there are numerous vaccines in works all over the world to tackle COVID-19. Experts believe that the minimum time required to test a vaccine is 12 to 18 months.

Trials are also going on for the repurposed drugs or the drugs which are useful for treating other diseases and might be capable against COVID-19: Some of these drugs are Hydroxychloroquine, chloroquine, Remdesivir, Dexamethasone, Lopinavir-ritonavir, and Convalescent plasma.

The only current solutions for tackling the pandemic are social distancing, hand wash, hygiene and face masks.

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