Thursday, July 30, 2020

Xenobots: The first ever ‘living’ robots

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Charvi Trivedi

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Xenobots: The first ever ‘living’ robots

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Global Views 360

Publication Date

July 30, 2020

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A xenobot in simulation and reality

A xenobot in simulation and reality | Source: Sam Kriegman via Computer-Designed Organisms

Creating robots using artificial intelligence has become quite normal in this century. But a robot built with an amalgamation of artificial intelligence and biology is quite enthralling. Researchers from University of Vermont and Tufts University collaborated to conceive a living robot called ‘Xenobot’.

This astounding, millimeter-wide chunk of technology is considered to be ‘living’ as it is created by stem cells from the embryo of Xenopus laevis, an African frog species. These stem cells were selected in such a way that they grew out to be heart and skin cells.

Prior to this, computer scientists at the University of Vermont ran an evolutionary algorithm, which imitates natural selection, on their supercomputer, which yielded the most suitable structures of the robot. After selecting the best designs, biologists at the Tufts University moulded the skin and heart cells into the forms which closely resembled the outputs of the algorithm, through microsurgery.

The resulting biological bodies looked like tiny aliens. "They're neither a traditional robot nor a known species of animal. It's a new class of artifact: a living, programmable organism" said Joshua Bongard, a computer scientist and robotics expert at the University of Vermont, who was involved in the research. Detailed results are published in the Proceedings of the National Academy of Sciences (PNAS) research paper on January 13, 2020.

Newly created xenobots were found to swim in any liquid medium for at least 10 days (or more if put in a nutrient-rich environment) without being fed with any nourishment, since the cells have a reserve of embryonic energy.

Another incredible facet of this technology is that it can revamp any of its parts efficiently upon damage. While technological pieces made out of plastic and metal might cause a lot of pollution after they are disposed of, xenobots are completely biodegradable, causing no harm to the environment. "These xenobots are fully biodegradable, when they're done with their job after seven days, they're just dead skin cells" said Bongard.

One might wonder how these miniscule cell blotches are helpful to us. Well, Xenobots may be very small in size but they can achieve feats which almost no huge, metal-made robot can.

These living robots will be useful in certain fields like medicine wherein they could be utilized to clear plague from our arteries. They can also be modelled with pouches which enables them to carry certain substances. This property can be used for delivering drugs in specific parts of our bodies. Xenobots can also be a boon in the field of cancer biology as they can help reprogramming tumors into normal cells.

Additionally, these tiny biological bodies can be oceans’ best friends. With contaminants like radioactive chemicals, plastics and microplastics creating havoc in the marine world, an immediate need to clean up our water bodies arises. Many xenobots were observed to be moving in circles (an attribute of the beating heart cells), which resembled a ‘clean-up’ motion. Hence, these tiny robots can be a perfect tool to eradicate microplastics from the oceans as well as eliminating nuclear wastes.

Although this technology may be promising, certain ethical questions arise with every technological development, especially those involving biological manipulations. If programmed in a certain way, xenobots can also take over natural biological functions (maybe nerve cells to hamper brain function) and this can be used for nasty purposes.

Michael Levin who directs the Center for Regenerative and Developmental Biology at Tufts said, “That fear is not unreasonable. When we start to mess around with complex systems that we don't understand, we're going to get unintended consequences”. Levin and Bongard are extensively working towards understanding how complex systems work. "There's all of this innate creativity in life. We want to understand that more deeply—and how we can direct and push it toward new forms" said UVM's Josh Bongard.

Like any new disruptive technological innovation, the Xenobots also have the potential to prove boon or bane for the humankind. Let's hope it turns out more boon than bane.

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February 4, 2021 4:46 PM

Electoral Processes in the US: Electing the President

The USA electoral process is a complex one; caucuses and primaries, followed by national conventions, general elections, formation of the electoral college and the selection of the president. Each step of this process has a lot of subtleties, which vary widely from state to state.

Caucuses and Primaries: This is the initial step of the selection of president. This stage of choosing occurs within a political party, where the party picks the candidate to rally behind.

In the state “Primary”', the registered members of political parties cast votes to allocate delegates for the presidential nominees of their parties. In some of the states this is done through caucuses, where groups are formed behind various potential candidates and there is discussion and persuasion between various groups. Republican party allocates all the delegates directly through primary or caucus, however the Democratic party allocates some Super-Delegates over and above the directly elected ones. These selected or allocated delegates are sent to the national party convention to represent their nominees.

In the process occurring between the primaries and caucuses to the selection of the potential electors is decided entirely by the party. The democrats, after the 1968 democratic convention, made a formal mechanism to reduce power of party leaders over the selection process and ways to represent minorities in the electors. This, however, backfired for the party as the delegates selected by primaries voted according to candidates and not the party, which led to the 1972 democratic Presidential candidate to win in only one state. The rules were then reformed and the concept of Super-Delegates was introduced. The Republican party also followed a somewhat similar trajectory, but did not impose as many restrictions on the delegate selection process, and never took measures to include the minorities.

National Conventions: Each parties’ delegates then choose a final presidential nominee at a national party convention. The nominee picks another person, who would be the vice president in the case the nominee wins. Here, there can be pledged or unpledged delegates; pledged ones are bound to support the potential candidates they chose in the previous round, while the unbound, or superdelegates can support anyone they choose.

Electoral College: After each of the parties have selected their presidential candidate, the candidate campaigns across the country to gain favor from the general public. There are speeches, rallies, debates, and other outreach activities, in which the candidates promote themselves. Meanwhile, the parties select some respective potential electors in each state, which are the people who get the last vote in the selection of the president. Each party forms a slate of potential electors according to the state..

General Election:After this, the general election occurs, in which the public votes for a president. However, the public does not directly vote for the president; they vote for the slate of electors for that political party for that state.

After the general election, the Electors are appointed to the state in two ways.. Electors from all the states then form the electoral college, which is the body that votes for the president. The electors are not legally bound to vote for the party they are pledged to, but can be fined or disqualified if they defect. Throughout USA history, though, more than 99% of the electors have voted as pledged.

The electoral college presently has 538 electors and the candidate who wins 270 or more electoral votes, wins the Presidential election.

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