Thursday, July 30, 2020

Xenobots: The first ever ‘living’ robots

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Charvi Trivedi

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Xenobots: The first ever ‘living’ robots

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Global Views 360

Publication Date

July 30, 2020

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A xenobot in simulation and reality

A xenobot in simulation and reality | Source: Sam Kriegman via Computer-Designed Organisms

Creating robots using artificial intelligence has become quite normal in this century. But a robot built with an amalgamation of artificial intelligence and biology is quite enthralling. Researchers from University of Vermont and Tufts University collaborated to conceive a living robot called ‘Xenobot’.

This astounding, millimeter-wide chunk of technology is considered to be ‘living’ as it is created by stem cells from the embryo of Xenopus laevis, an African frog species. These stem cells were selected in such a way that they grew out to be heart and skin cells.

Prior to this, computer scientists at the University of Vermont ran an evolutionary algorithm, which imitates natural selection, on their supercomputer, which yielded the most suitable structures of the robot. After selecting the best designs, biologists at the Tufts University moulded the skin and heart cells into the forms which closely resembled the outputs of the algorithm, through microsurgery.

The resulting biological bodies looked like tiny aliens. "They're neither a traditional robot nor a known species of animal. It's a new class of artifact: a living, programmable organism" said Joshua Bongard, a computer scientist and robotics expert at the University of Vermont, who was involved in the research. Detailed results are published in the Proceedings of the National Academy of Sciences (PNAS) research paper on January 13, 2020.

Newly created xenobots were found to swim in any liquid medium for at least 10 days (or more if put in a nutrient-rich environment) without being fed with any nourishment, since the cells have a reserve of embryonic energy.

Another incredible facet of this technology is that it can revamp any of its parts efficiently upon damage. While technological pieces made out of plastic and metal might cause a lot of pollution after they are disposed of, xenobots are completely biodegradable, causing no harm to the environment. "These xenobots are fully biodegradable, when they're done with their job after seven days, they're just dead skin cells" said Bongard.

One might wonder how these miniscule cell blotches are helpful to us. Well, Xenobots may be very small in size but they can achieve feats which almost no huge, metal-made robot can.

These living robots will be useful in certain fields like medicine wherein they could be utilized to clear plague from our arteries. They can also be modelled with pouches which enables them to carry certain substances. This property can be used for delivering drugs in specific parts of our bodies. Xenobots can also be a boon in the field of cancer biology as they can help reprogramming tumors into normal cells.

Additionally, these tiny biological bodies can be oceans’ best friends. With contaminants like radioactive chemicals, plastics and microplastics creating havoc in the marine world, an immediate need to clean up our water bodies arises. Many xenobots were observed to be moving in circles (an attribute of the beating heart cells), which resembled a ‘clean-up’ motion. Hence, these tiny robots can be a perfect tool to eradicate microplastics from the oceans as well as eliminating nuclear wastes.

Although this technology may be promising, certain ethical questions arise with every technological development, especially those involving biological manipulations. If programmed in a certain way, xenobots can also take over natural biological functions (maybe nerve cells to hamper brain function) and this can be used for nasty purposes.

Michael Levin who directs the Center for Regenerative and Developmental Biology at Tufts said, “That fear is not unreasonable. When we start to mess around with complex systems that we don't understand, we're going to get unintended consequences”. Levin and Bongard are extensively working towards understanding how complex systems work. "There's all of this innate creativity in life. We want to understand that more deeply—and how we can direct and push it toward new forms" said UVM's Josh Bongard.

Like any new disruptive technological innovation, the Xenobots also have the potential to prove boon or bane for the humankind. Let's hope it turns out more boon than bane.

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February 4, 2021 5:00 PM

Stonewall Riots: A Pillar In The Movement For American LGBTQIA+ Rights

The Stonewall Riots are globally remembered as the cornerstone of Pride Month, and rightfully so. Fifty-one years ago, a routine police raid on Stonewall Inn, a gay bar in New York turned into an upheaval against homophobic society, laws, and policing.

In the early hours of June 28, 1969, a police raid— often conducted on secret or private bars that exclusively served LGBTQIA+ patrons— turned its head on the New York Police Department.

The Stonewall riot in 1969 | Source: David via Flickr

Some accounts say that the pivotal moment came when few of the lesbians who were brutally shoved into a police wagon showed resistance. In response, the crowd lit up in anger and resistance. Instead of running away to save themselves, the patrons fought back, even leading to the police barricading themselves within the bar itself as they waited for backup.

The Stonewall riot in 1969 | Source: David via Flickr

News of the clash spread and more people gathered, throwing anything they could find: nickels, garbage cans, broken bottles, and yes, bricks too, though ‘the first brick’ may have been more myth than real. Eventually, it took the fire department and a riot squad to quell the riots on the first night.

Defiant, Stonewall reopened the next evening, and the confrontation between police and community members continued for the rest of the week, drawing hundreds and upto thousands of community members. A total of twenty one protestors were arrested over the week, with the majority being arrested on the first night itself.

It’s hard to pinpoint what exactly led to the Stonewall riots, or the status that it earned in present-day Pride and LGTBQ+ liberation movements. The movement for LGTBQ+ rights existed before Stonewall (if relatively subdued relative to what came after), and so did the concept of ‘Pride,’ in the form of ‘Personal Rights in Defense and Education’ (PRIDE) that went on to become the Advocate magazine.

Stonewall wasn’t even the first time the community clashed with the police. It has been postulated that the act of naming, “the first to be called the first,” and the decision of organizers to commemorate its anniversary in the form of ‘Christopher Street Liberation Day’ contributed largely to Stonewall becoming a permanent and popular fixture in LGBTQIA+ history and collective memory.  

Regardless of the contributing factors, the cultural impact of Stonewall on American and Western LGBTQIA+ communities was immediate and intense. It became the epicentre of a louder, more radical movement. The community had tried it the ‘respectable’ way through organisations such as Mattachine, but it didn’t get them anywhere.

The number of LGTBQ+ focused organisations and magazines soared after Stonewall, going from around two dozen to four hundred. These included radical organisations such as the Gay Liberation Front and Radicalesbians.

The year after Stonewall, Sylvia Rivera and Marsha P. Johnson, who were present at the riots and are considered transgender icons, created the Street Transvestite Action Revolutionaries (STAR), which focused on struggles of drag queens and trans and gender-non-conforming youth who often lived on the streets.

Stonewall Inn as it existed no longer stands, but the new Stonewall Inn in the same street and the park across it have been recently declared as a historic national monument.

The old Stonewall was not a luxurious bar in terms of drinks or furnishings. It was not a place frequented by upper or middle class, white, cisgender gay men. Being a dance bar whose patrons included working class or homeless LGBTQIA+ people and drag queens, it was often looked down upon. All of that changed in one week, and the spirit that shone in Stonewall that night continues to resonate and be celebrated in the hearts of all LGBTQIA+ people.

In light of the ongoing Black Lives Matter protests and the rioting that happened alongside, many LGBTQIA+ people on social media have responded to criticism by reminding people of Stonewall, and how the “first Pride” was a riot led by Black and Latin transgender women, gender non-conforming youth, and other LGBTQIA+ people of colour, the very people whose history and resistance has often been white-washed, diminished, or erased altogether.

As said by Martin Luther King Jr., “A riot is the language of the unheard.”

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