Thursday, July 30, 2020

Xenobots: The first ever ‘living’ robots

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Charvi Trivedi

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Xenobots: The first ever ‘living’ robots

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Global Views 360

Publication Date

July 30, 2020

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A xenobot in simulation and reality

A xenobot in simulation and reality | Source: Sam Kriegman via Computer-Designed Organisms

Creating robots using artificial intelligence has become quite normal in this century. But a robot built with an amalgamation of artificial intelligence and biology is quite enthralling. Researchers from University of Vermont and Tufts University collaborated to conceive a living robot called ‘Xenobot’.

This astounding, millimeter-wide chunk of technology is considered to be ‘living’ as it is created by stem cells from the embryo of Xenopus laevis, an African frog species. These stem cells were selected in such a way that they grew out to be heart and skin cells.

Prior to this, computer scientists at the University of Vermont ran an evolutionary algorithm, which imitates natural selection, on their supercomputer, which yielded the most suitable structures of the robot. After selecting the best designs, biologists at the Tufts University moulded the skin and heart cells into the forms which closely resembled the outputs of the algorithm, through microsurgery.

The resulting biological bodies looked like tiny aliens. "They're neither a traditional robot nor a known species of animal. It's a new class of artifact: a living, programmable organism" said Joshua Bongard, a computer scientist and robotics expert at the University of Vermont, who was involved in the research. Detailed results are published in the Proceedings of the National Academy of Sciences (PNAS) research paper on January 13, 2020.

Newly created xenobots were found to swim in any liquid medium for at least 10 days (or more if put in a nutrient-rich environment) without being fed with any nourishment, since the cells have a reserve of embryonic energy.

Another incredible facet of this technology is that it can revamp any of its parts efficiently upon damage. While technological pieces made out of plastic and metal might cause a lot of pollution after they are disposed of, xenobots are completely biodegradable, causing no harm to the environment. "These xenobots are fully biodegradable, when they're done with their job after seven days, they're just dead skin cells" said Bongard.

One might wonder how these miniscule cell blotches are helpful to us. Well, Xenobots may be very small in size but they can achieve feats which almost no huge, metal-made robot can.

These living robots will be useful in certain fields like medicine wherein they could be utilized to clear plague from our arteries. They can also be modelled with pouches which enables them to carry certain substances. This property can be used for delivering drugs in specific parts of our bodies. Xenobots can also be a boon in the field of cancer biology as they can help reprogramming tumors into normal cells.

Additionally, these tiny biological bodies can be oceans’ best friends. With contaminants like radioactive chemicals, plastics and microplastics creating havoc in the marine world, an immediate need to clean up our water bodies arises. Many xenobots were observed to be moving in circles (an attribute of the beating heart cells), which resembled a ‘clean-up’ motion. Hence, these tiny robots can be a perfect tool to eradicate microplastics from the oceans as well as eliminating nuclear wastes.

Although this technology may be promising, certain ethical questions arise with every technological development, especially those involving biological manipulations. If programmed in a certain way, xenobots can also take over natural biological functions (maybe nerve cells to hamper brain function) and this can be used for nasty purposes.

Michael Levin who directs the Center for Regenerative and Developmental Biology at Tufts said, “That fear is not unreasonable. When we start to mess around with complex systems that we don't understand, we're going to get unintended consequences”. Levin and Bongard are extensively working towards understanding how complex systems work. "There's all of this innate creativity in life. We want to understand that more deeply—and how we can direct and push it toward new forms" said UVM's Josh Bongard.

Like any new disruptive technological innovation, the Xenobots also have the potential to prove boon or bane for the humankind. Let's hope it turns out more boon than bane.

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February 4, 2021 5:06 PM

Italian Mafia make merry amidst the COVID-19 pandemic

Italy was the first European nation to encounter the coronavirus and it still is one of the worst hit nations in Europe. The country has been battling with an economic decline and rising unemployment for a few years now. However, the COVID-19 pandemic hitting the country was like rubbing salt in Italy’s wounds.

The strict lockdown imposed by the government in Italy has had an adverse effect on a lot of people particularly the small scale and the medium scale business owners. Thus, a lot of people in Italy have resorted to desperate measures. The Italian mafia have made merry of the situation by providing these people with the much-needed aid they have been looking for.

Even as the country struggles to pull itself together, the mafia have made inroads in acquiring influence over the locals by distributing food packets to poor families with no source of income. There have been videos surfacing from the southern regions which suggest that the mafia have been actively involved in delivering essential items to the people.

In Palermo, a mafia gang member, who has been distributing food to the poor, says "People ring me and they cry over the phone,". He further tells, "They say their children can't eat. A young woman has been calling me every single day. She has five kids and doesn't know how to feed them."

However, the Italian mafia has been employing the tactics of exploiting vulnerability of the locals in the face of economic crisis for a long time. The COVID-19 pandemic was yet another opportune moment for them to capitalise.

"The mafia has never done anything out of generosity. That concept doesn't exist for them," says Enza Rando who works for an anti-mafia organisation. "All they know is I'll scratch your back if you scratch mine."

A report by  the Global Initiative Against Transnational Organized Crime (GI-TOC), based on virtual round table discussion between top anti mafia officials and activists suggests that the healthcare sector as well as the manual laborers and service staff who work mostly cash jobs are the most vulnerable to the mafia influence during the COVID-19 pandemic.

As per the national anti-corruption authority ANAC the mafia corruption has been a big setback to the COVID-hit Italian economy. "They are taking advantage of the emergency situations like the current one, with devastating effects on the economic system and on healthy businesses, already hard hit by the crisis," said ANAC President Francesco Merlon.

Sergio Nazzaro, a journalist, writer and adviser to the Parliamentary Anti-Mafia Commission says, ”The people who are jobless don’t care about the mafia, corruption or anything, but they see the state only talking, and from the mafia (they see) money, and I fear that at the end of all this we are going to see how much the mafia managed to buy while we were in crisis.” He stresses that the state will have to provide economic stability to the people if it hopes to eliminate the mafia influence.

Father Luigi Ciotti, an Italian priest and well-known anti-mafia activist pointed out three key areas that need to be monitored for mafia activity during the pandemic. The first is the increase in drug trafficking. The second one is new products like face masks, disinfectants etc which are suddenly in demand and provide heavy profits and third the predatory money lending.

It is quite clear that the Italian government needs to come up with strong economic reforms that ensure stability and security for its people if it hopes to counter the mafia influence. Otherwise, the mafia will always be there to trap vulnerable people by proving to be their benefactors in the short run only to exploit at a later stage.

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