Thursday, July 30, 2020

Xenobots: The first ever ‘living’ robots

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Charvi Trivedi

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Xenobots: The first ever ‘living’ robots

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Global Views 360

Publication Date

July 30, 2020

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A xenobot in simulation and reality

A xenobot in simulation and reality | Source: Sam Kriegman via Computer-Designed Organisms

Creating robots using artificial intelligence has become quite normal in this century. But a robot built with an amalgamation of artificial intelligence and biology is quite enthralling. Researchers from University of Vermont and Tufts University collaborated to conceive a living robot called ‘Xenobot’.

This astounding, millimeter-wide chunk of technology is considered to be ‘living’ as it is created by stem cells from the embryo of Xenopus laevis, an African frog species. These stem cells were selected in such a way that they grew out to be heart and skin cells.

Prior to this, computer scientists at the University of Vermont ran an evolutionary algorithm, which imitates natural selection, on their supercomputer, which yielded the most suitable structures of the robot. After selecting the best designs, biologists at the Tufts University moulded the skin and heart cells into the forms which closely resembled the outputs of the algorithm, through microsurgery.

The resulting biological bodies looked like tiny aliens. "They're neither a traditional robot nor a known species of animal. It's a new class of artifact: a living, programmable organism" said Joshua Bongard, a computer scientist and robotics expert at the University of Vermont, who was involved in the research. Detailed results are published in the Proceedings of the National Academy of Sciences (PNAS) research paper on January 13, 2020.

Newly created xenobots were found to swim in any liquid medium for at least 10 days (or more if put in a nutrient-rich environment) without being fed with any nourishment, since the cells have a reserve of embryonic energy.

Another incredible facet of this technology is that it can revamp any of its parts efficiently upon damage. While technological pieces made out of plastic and metal might cause a lot of pollution after they are disposed of, xenobots are completely biodegradable, causing no harm to the environment. "These xenobots are fully biodegradable, when they're done with their job after seven days, they're just dead skin cells" said Bongard.

One might wonder how these miniscule cell blotches are helpful to us. Well, Xenobots may be very small in size but they can achieve feats which almost no huge, metal-made robot can.

These living robots will be useful in certain fields like medicine wherein they could be utilized to clear plague from our arteries. They can also be modelled with pouches which enables them to carry certain substances. This property can be used for delivering drugs in specific parts of our bodies. Xenobots can also be a boon in the field of cancer biology as they can help reprogramming tumors into normal cells.

Additionally, these tiny biological bodies can be oceans’ best friends. With contaminants like radioactive chemicals, plastics and microplastics creating havoc in the marine world, an immediate need to clean up our water bodies arises. Many xenobots were observed to be moving in circles (an attribute of the beating heart cells), which resembled a ‘clean-up’ motion. Hence, these tiny robots can be a perfect tool to eradicate microplastics from the oceans as well as eliminating nuclear wastes.

Although this technology may be promising, certain ethical questions arise with every technological development, especially those involving biological manipulations. If programmed in a certain way, xenobots can also take over natural biological functions (maybe nerve cells to hamper brain function) and this can be used for nasty purposes.

Michael Levin who directs the Center for Regenerative and Developmental Biology at Tufts said, “That fear is not unreasonable. When we start to mess around with complex systems that we don't understand, we're going to get unintended consequences”. Levin and Bongard are extensively working towards understanding how complex systems work. "There's all of this innate creativity in life. We want to understand that more deeply—and how we can direct and push it toward new forms" said UVM's Josh Bongard.

Like any new disruptive technological innovation, the Xenobots also have the potential to prove boon or bane for the humankind. Let's hope it turns out more boon than bane.

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February 4, 2021 5:10 PM

Why the people are protesting in Hong Kong

Hong Kong is a special administrative region of the People’s Republic of China located on the Eastern Pearl River Delta of the South China Sea. From 1842 to 1997, the region was under the control of the Britishers.

In 1997 the  sovereignty of Hong Kong was transferred to China with the principle of “one country, two systems” which provided some degree of autonomy for Hong Kong. This system was supposed to be in force for a period of minimum fifty years from 1997 to 2047. However, under President Xi Jinping, China has been aggressively making such rules and regulations which increase the influence of mainland China on administration of Hong Kong.

In June 2020, China started implementing a new national security law for which potentially severely limits the independence of the judiciary of Hong Kong. Under the proposed law, Hong Kong’s Chief Executive, who is answerable to Beijing, gets the power to appoint judges for specific security cases. It also calls for setting up a security agency in Hong Kong to resolve existing conflicts and challenges faced by Beijing with respect to Hong Kong.

China defended the law by citing that it would prevent and punish secession, subversion as well as foreign infiltration. Beijing has argued that these three factors are responsible for fuelling unrest in the city since last year. Critics however have very different opinions regarding the law. For them this law directly attacks the relative autonomy granted to Hong Kong after Britain handed it back to China in 1997.

The law can potentially be employed to target anti-government protests and other forms of dissent in the region of Hong Kong. It has instilled fear in the minds of the Hong Kong residents that the Chinese Communist Party is trying to curb the freedom of speech and protest in the region in an effort to bring Hong Kong under its authoritarian rule.

Many protesters are of the belief that the local governments of Hong Kong are no longer autonomous and act on the whims of Beijing. They accuse the city's top leader, Chief Executive Carrie Lam, who is appointed by Beijing, of acting only in the interest of mainland China while ignoring to safeguard the autonomy of Hong Kong.

The protests Hong Kong witnessed in May 2020, were quite similar to the ones the city witnessed almost a year ago when China proposed an extradition law for Hong Kong. The law was eventually scrapped after a flurry of protests. However the protest against the territory’s existing leadership turned into a protest against Chinese ruling party’s efforts to merge Hong Kong with mainland China.

At its core, the protest movement is aimed at protecting Hong Kong’s autonomy and resisting encroachment from the mainland. However, China’s adamant approach in bringing Hong Kong under the mainland amidst a falling economy and rising agitation and police brutality has had a negative impact on the residents.

Many Hong Kong protesters have started moving to countries who are willing to adopt them over fears of being under scrutiny from the Chinese government. Many of the skilled workers are now looking at ways to exit the city and move to better alternatives. More than half of the people from the age group of 18 to 24 are considering options outside of Hong Kong owing to the uncertainty surrounding the region’s fate.

Despite the protest by citizens and condemnation and actions by the US, Britain and other Western countries, it seems unlikely that China is going to halt its efforts to dismantle the autonomy of Hong Kong and effectively merge it with the mainland China.

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