Monday, July 13, 2020

The Coronavirus Disease

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Hardi Talwani

Article Title

The Coronavirus Disease

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Global Views 360

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July 13, 2020

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Computer generated representation of COVID-19 virions (SARS-CoV-2) under electron microscope

Computer generated representation of COVID-19 virions (SARS-CoV-2) under electron microscope | Source Felipe Esquivel Reed via Wikimedia

Severe acute respiratory syndrome-Coronavirus 2 (SARS-CoV-2) is a novel virus from the family of coronaviruses which causes COVID-19 i.e. Coronavirus Disease-2019. It is the successor of the SARS-CoV-1 which caused the SARS outbreak in the year 2003-2004. This is a positive-sense single-stranded RNA virus which has rapid mutation properties.

The etymology of the name suggests that 'Corona' comes from the Latin word corōna meaning crown, garland, or a wreath. When seen under an Electron Microscope, the virion which has a diameter of 50-200 nanometres looks like the solar corona hence named Coronavirus.

When the virus enters the body; it attaches itself to the binding site or the ACE 2 receptors of healthy lung cells through its spike protein. Then it enters the cell via this attachment and causes apoptosis or cell death. The virus also affects organs other than lungs such as the brain, heart and kidneys. The multiple impact points make it problematic for the researchers to create a vaccine in addition to its rapid mutation properties.

The disease might have a zoonotic origin i.e. the transmission occurs from animals to humans. On comparing the genomic sequences the Human Coronavirus strain is found to be 96% identical to Bat Coronavirus samples and 92% similar to the Pangolins samples. Human transmission of the disease takes place via air droplets when the infected person is coughing, sneezing or talking.

The first cases of this respiratory illness were reported to the World Health Organization (WHO) from Wuhan City, Hubei Province, China, on 31 December 2019. It is the first severe outbreak since the 2009 H1N1 Influenza Pandemic. Initially, it was supposed that the site of origination is Huanan Seafood Wholesale Market but, in May 2020 the negative samples tested, by  Chinese Center for Disease Control and Prevention, from the livestock market suggested that it was the site of the super spreading of the virus.

SARS-CoV-2 is known to have an average reproduction number of 2.2-2.6 which means that, on an average, one infected person can spread the infection to 2-3 people. Although if measures like social distancing are put into use, to reduce the exposure of the infected population, it leads to a significant reduction in transmission rates. The infection fatality rate (IFR) of COVID-19 in various studies till 16th June 2020 was projected to range 0.60% to 1% of infected people . However few studies suggested the IFR as high as 3.6%.

The testing of an individual takes place through a method known as real-time Reverse transcription Polymerization Chain reaction (rRT-PCR). The process of obtaining strains and testing the patients usually involves nasal swabs or sputum swabs; the results come in within a span of a few hours to a couple of days.

Currently, there are no known vaccines available for the virus or any specific antiviral treatments, but there are numerous vaccines in works all over the world to tackle COVID-19. Experts believe that the minimum time required to test a vaccine is 12 to 18 months.

Trials are also going on for the repurposed drugs or the drugs which are useful for treating other diseases and might be capable against COVID-19: Some of these drugs are Hydroxychloroquine, chloroquine, Remdesivir, Dexamethasone, Lopinavir-ritonavir, and Convalescent plasma.

The only current solutions for tackling the pandemic are social distancing, hand wash, hygiene and face masks.

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February 4, 2021 4:55 PM

Suppressing the Minority Voting: An effective discrimination tactic of the US Conservatives

The recent protests over George Floyd’s death and reactions of the conservatives against the protest laid bare the systemic injustice and oppression faced by the people of color in the USA.

The other, albeit invisible form of discrimination perpetuated by the conservative political establishment in the USA is “Minority Voter Suppression”.

Though it may seem improbable that long after the Jim Crow laws are junked and Civil Right Laws are in place, the effort to disenfranchise the Black people is still going on.

The major piece of legislation which protected minorities from electoral exploitation was the Voter Registration Act which underpins the basic ideal of a universal adult franchise by specifically addressing and combating voting discrimination.

To ensure the representation to minority communities, this act mandated that “At-Large Elections”, where the whole of the jurisdiction elects all of the city council, were replaced by the single member districts in which each community selects a person to represent them in the city council.

It was also prohibited to draw the voting district in such a way that  minorities could be clubbed in only a few of the districts. It was also made mandatory for those states which have a history of discrimination to get pre-clearance from the justice department before changing their voting laws.

This law, however, lost its power in a process which began in 1980. In 1980 the Supreme Court ruled that at-large elections were not unconstitutional, on their own. In 1995, the Court began restricting the construction of majority minority districts on grounds that it segregates people on the basis of race.

In 2008, the court ruled that a photo voter ID law in Indiana was constitutional and was in state interest to protect against voter fraud (research shows that photo voter IDs provide disincentive to vote for people of color). The voter ID law requires the voters to have a government-issued photo ID to cast a ballot.

In 2013, the Supreme Court scrapped the part of the law which stated that some states (which had an alleged history of discrimination) needed federal preclearance in any changes of their voting laws, meaning that the state laws would need approval from the federal government before being put into practice. This was done so citing that the methods which determined discriminatory states were invalid.

All of these slowly chipped away at the laws, and especially the 2013 Shelby County vs Holder case which led to a host of issues whVoter Suppression is Still One of the Greatest Obstacles to a More Just Americaich directly/indirectly keep a significant proportion of minorities from voting. Few of such actions are closure or relocation of precincts in majority black areas, purge of minority voters from the voter lists, and elimination of Sunday early voting days which are preferred by black voters.

There have been attempts to restrict registration drives in Tennessee on the basis that many of the forms were incomplete.

There have also been laws enacted which needed people to participate regularly in elections to keep their voting rights and reply to a letter sent to their residence, which makes it difficult for Black and Hispanics due to obscure areas and the fact that they’re half as likely than other people to get a day off work to vote.

The governor of Georgia, Brian Kemp, has been accused of using intimidation tactics to scare minority communities.

In Texas, the acting secretary of state said that he had a list of 95,000 non-citizens who were registered for voting in the state, and 58,000 of them had already cast a vote. That claim was proven untrue when it was noted that there were tens of thousands of people who were naturalized citizens.

In many states, felons are not allowed to vote even after they have served their sentence, and in Florida felons are allowed to vote only if they have paid an array of fees after serving their sentence, which sets an economic bar on their ability to vote.

This is evident that forces working against the equal rights for the minority communities are still working at full force to reverse the gains of civil right movements. The fight for the unhindered voting rights for the minority communities in the USA at the social, political, and judicial front will continue in the foreseeable future.

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